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pentobarbital will reduce the extent or effect of fosaprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Observe Closely (1)pentobarbital will decrease the level or impact of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or impact of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Coadministration of fentanyl with CYP3A4 inducers could lead on to your minimize in fentanyl plasma concentrations, not enough efficacy or, potentially, advancement of the withdrawal syndrome inside a patient that has developed physical dependence to fentanyl.
pentobarbital will minimize the level or impact of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Significance Unfamiliar.
pentobarbital will minimize the level or impact of nisoldipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
fentanyl transdermal and pentobarbital both of those raise sedation. Prevent or Use Alternate Drug. Restrict use to sufferers for whom alternative treatment solutions are insufficient
If this drug is employed for the duration of pregnancy, or In case the affected person results in being Expecting though taking this drug, the affected individual ought to be apprised from the prospective hazard on the fetus
pentobarbital will decrease the extent or result of levoketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
pentobarbital will lessen the extent or impact of rabeprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
pentobarbital will minimize the extent or impact of zolpidem by influencing read more hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.
Contraindicated (1)pentobarbital will reduce the level or impact of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with potent CYP3A4 inducers is not proposed
pentobarbital will reduce the level or impact of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic result of elbasvir/grazoprevir can be minimized if coadministered with solid CYP3A inducers which is for that reason contraindicated.
pentobarbital will lower the level or influence of armodafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.